Alternative splicing in the voltage - gated sodium channel 1 DmNav regulates activation , inactivation and persistent 2 current . 3
نویسندگان
چکیده
Alternative splicing in the voltage-gated sodium channel 1 DmNav regulates activation, inactivation and persistent 2 current. 3 Wei-Hsiang Lin*, Duncan E Wright*, Nara I Muraro and Richard A. Baines 4 Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester, UK. 5 *authors contributed equally 6 7 8 Pages: 45 9 Figures: 8 10 Tables: 5 11 supplementary material: 2 Figures 12 13 14 15 16 Running Head: splicing of a voltage-gated Na channel 17 18 19 20 21 Address for correspondence: 22 23 Richard Baines 24 Faculty of Life Sciences, 25 University of Manchester, 26 Oxford Road, 27 Manchester, 28 United Kingdom. 29 [email protected] 30 Tel: + 44 161 2755365 31 32
منابع مشابه
Alternative splicing in the voltage-gated sodium channel DmNav regulates activation, inactivation, and persistent current.
Diversity in neuronal signaling is a product not only of differential gene expression, but also of alternative splicing. However, although recognized, the precise contribution of alternative splicing in ion channel transcripts to channel kinetics remains poorly understood. Invertebrates, with their smaller genomes, offer attractive models to examine the contribution of splicing to neuronal func...
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